Managing Medication Side Effects: Solutions for Common Issues

While psychiatric medications can be life-changing, they sometimes bring side effects that can interfere with daily life. When stopping or lowering the dose isn’t an option, targeted solutions can help patients stay on their treatment while minimizing discomfort. Here’s a closer look at strategies for managing three common medication-related side effects: nausea, sweating, and dry mouth.

Nausea: A Temporary but Frustrating Problem

Nausea is one of the main reasons people stop medications early, even though it often fades with time. A slow dose increase can reduce nausea significantly, but when it happens, a few simple steps can help:

• Take medication immediately after a meal (not just with food).

• Ginger supplements—backed by clinical trials—can be effective. Capsules taken about an hour before eating tend to work best.

• Ondansetron (Zofran) is a well-tolerated prescription option if nausea persists, though it may cause constipation.

• Metoclopramide is another option but is used less frequently.

Sweating: More Than Just an Annoyance

Excess sweating is a common but underreported side effect of antidepressants. Fortunately, certain medications can help:

• Glycopyrrolate, an anticholinergic that doesn’t affect cognition, is often the first-line option.

• Terazosin, an alpha-1 antagonist, also reduces sweating but carries a small risk of lowering blood pressure.

• Oxybutynin and benztropine are sometimes used, but they can impair memory and focus, making them less ideal for many patients.

Dry Mouth: A Hidden but Potentially Serious Concern

Dry mouth is more than just an inconvenience—it increases the risk of cavities and bad breath. Many people don’t bring it up, but addressing it early can prevent long-term issues.

• Dental care is key: Regular cleanings, brushing twice daily, and avoiding alcohol-based mouthwashes can help.

• Xylitol gum or lozenges (used at least four times daily) reduce bacteria and freshen breath.

• Biotene mouthwash or gel provides symptom relief by keeping the mouth moist.

• Pilocarpine eye drops (4%), diluted in water and swished around the mouth (then spit out), offer a localized way to increase saliva without systemic side effects.

Final Thoughts

Medication side effects don’t have to mean stopping treatment. Many symptoms can be managed with small adjustments or targeted solutions, allowing people to stay on their regimen while improving their overall comfort and quality of life. If a side effect is interfering with daily activities, personalized strategies can help strike the right balance between effectiveness and tolerability.